Our Pharmaceuticals business discovers, develops and makes medicines to treat a broad range of the world's most common acute and chronic diseases.
The business generated sales of £16.1 billion in 2016, representing 58% of the total turnover of the Group.
The business is made up of innovative and established medicines and holds leading positions in respiratory disease and HIV. In our Pharmaceuticals R&D organisation, 80% of research spending focuses on two current therapy areas: respiratory and HIV/infectious diseases; and two potential areas: oncology and immuno-inflammation.
The global pharmaceuticals market is vast. The biggest areas of growth over recent years have been from the emerging markets and Asia Pacific regions.
This trend of increasing demand is expected to continue as the world’s population grows, economies in the emerging markets become more prosperous and global changes in lifestyles affect long-term health.
Our Pharmaceuticals business creates value by researching and manufacturing innovative products and making these as widely accessible as possible to countries at all levels of income and development.
While we continue to have a strong presence in developed markets such as the USA and Europe, we are increasing investment in emerging markets, including Africa, where we see significant growth potential.
Our Pharmaceuticals portfolio
Our portfolio is made up of innovative and established medicines and we have leading global positions in respiratory disease and HIV.
We have been a leader in respiratory disease for over 40 years and have a portfolio of mature products. In recent years, we have strengthened and broadened our respiratory portfolio with the addition of new medicines including an inhaled corticosteroid (ICS) and long-acting beta2 agonist (LABA) combination, a long-acting muscarinic antagonist (LAMA) and LABA dual bronchodilator.
Our HIV business is managed through ViiV Healthcare, a global specialist company in HIV that we majority own, with Pfizer and Shionogi as the other shareholders. ViiV Healthcare is now a leading global company in HIV and has had significant recent success with regulatory approval and industry leading launches of new medicines. ViiV Healthcare has a number of other antiretroviral medicines in clinical development.
In addition to respiratory and HIV, we have a portfolio of other innovative Pharmaceutical products for the treatment of conditions such as lupus, benign prostatic hyperplasia, type 2 diabetes and bacterial infections.
We also have an Established Products Portfolio (EPP) which includes mature medicines in the areas of anti-infectives, allergy, central nervous system, dermatology, respiratory and urology. These products are an important part of our Emerging Markets business where the GSK brand is an important differentiator.
Focus on best science
If we are to continue to discover new medicines and get them to the patients who need them as quickly as possible, we must invest in research. In 2016, £2.6 billion was invested into the search for new pharmaceutical medicines.
We expect important data on between 20-30 assets in areas including HIV, respiratory, Immuno-inflammation and oncology.
The journey to discovering and developing new medicines is lengthy, expensive and subject to a high rate of failure. Learn more about how we discover new medicines.
We are exploring different approaches to promote – and speed up – innovation in our labs. Having broken down the traditional, R&D model, our scientists now work in smaller units focused on specific areas of research. This encourages greater entrepreneurialism and accountability. These groups are tasked with seeking out the biological targets involved in disease and creating molecules or biopharmaceuticals that will ultimately become new medicines.
We also know that we won’t discover everything inside our own labs and that we need to partner with other companies, academic institutions and research charities. We currently have research collaborations with more than 1,500 external organisations.
We also recognise our responsibility to meet society’s expectations to invest in disease areas where the science is difficult or where the typical business model to reward innovation may not be relevant; one example being our antibiotics research. We are also one of the few healthcare companies researching the World Health Organization’s three priority diseases - HIV/AIDS, tuberculosis and malaria.
Other business areas
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Corporate Executive Team
The Corporate Executive Team manages our activities, and each member is responsible for a specific part of the business
It began when Plough Court Pharmacy was established in 1715. Discover GSK's journey through the centuries that led to the organisation we know today
Our prescription medicines
Our pharmaceuticals business discovers, develops and makes medicines to treat a broad range of the world's most common acute and chronic diseases
How we discover our new products
Find out how we discover and develop new products, and how patient safety is always our number one priority