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Ozone depleting substances in manufacturing

A small proportion of the CFC used to manufacture Metered Dose Inhalers (MDIs) is released during the manufacturing process. We are working to eliminate use of ozone depleting substances (ODSs) in MDIs by switching to HFC and dry powder inhalers (see metered dose inhalers).

Ozone depletion potential from production use
chart: Ozone Depletion Potential from Production Use

Year
Production
 
(million kg)
2001
0.183
2002
0.121
2003
0.072
2004
0.059


Per unit sales as percentage of 2001 baseline
2001
2002
2003
2004
2005
100%
63.8%
37.4%
32.5%
50.0%

Ozone depleting substances released from production activities
Substance
2002
2003
2004
CFC11/R11
12,634
1.0
12,634
CFC12/R12
46,304
1.0
46,304
1,1,1 TRICHLOROETHANE
265
0.1
27
METHYL BROMIDE
590
0.6
354


Ozone depletion potential from production by business
chart: Ozone Depletion Potential from Production by Business


Ozone depleting substances released from production activities by business
 
2001
2002
2003
2004
 
(thousand kg CFC-11 equivalent)
01. R&D
0.00
0.00
0.00
0.00
02. Biologicals
0.00
0.00
0.00
0.00
03. Consumer healthcare
0.00
0.00
0.00
0.00
04. New product and global supply
111.87
74.59
42.35
47.36
05. Regional pharma supply
70.53
46.19
29.15
11.61
06. Primary supply and antibiotics
0.00
0.50
0.40
0.35
07. Commercial
0.00
0.00
0.00
0.00
08. Other
1.09
0.00
0.00
0.00

Total ozone depletion potential from production decreased by 18.1% since 2003 (67.8% since 2001). Ozone depletion potential from production per unit sales decreased by 13.1% since 2003 (67.5% since 2001) - meaning we have exceeded our 2005 target of a 50% reduction per unit sales since 2001.

As production of CFC-containing MDIs decreases, the amount of CFC lost during production also declines. We will no longer manufacture CFC-containing MDIs in the US after 2005 and in Europe after 2006. We will continue to manufacture them in Bangladesh, China, India and Pakistan until the end of 2009.


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