{"magazineArticle":{"contentWrapper":{"hideReadArticle":false,"headline":"‘AI has already transformed medical innovation. Let’s not let fears of technology stop us from realising its incredible potential’","datePublished":"2023-10-18T00:00:00","datePublishedFormatted":"18 October 2023","parentHref":{"text":"Behind the Science magazine","href":"/en-gb/behind-the-science-magazine/","openInNewWindowText":null},"nextArticle":{"text":"Next article","href":"/en-gb/behind-the-science-magazine/biomarker-testing-ai-tumours-hepatitis-respiratory-cancer/","openInNewWindowText":null},"carouselTitle":"","readTimeMins":3,"captions":{"listenToArticle":"Listen to this article","readTime":"min read time","relatedTags":"Related tags"},"heroImage":{"src":"/media/jznms4j0/gettyimages-1455924944.jpg?format=webp&v=1dba2eb9dce0320&hmac=265c4121f54b6375b125b300277bb2116f1f438150ecf2614ffa4ec720b9a772","alt":"Scientist looking at data","darkModeSrc":"/media/jznms4j0/gettyimages-1455924944.jpg?format=webp&quality=50&v=1dba2eb9dce0320&hmac=92b784ea4e4fbe2aec03128a0f0513563bf63b6eef0d5eeaf9d860f5d5bf90c6"},"author":null,"articleType":"Opinion","videoType":null,"topics":["Early Science and Technology","AI"],"introText":""},"components":[{"type":"rich-text","text":"<p><strong>There has always been fear about new technologies, argue GSK’s leading AI experts Kim Branson, Robert Vandersluis and Jeremy England, but that shouldn’t hold us back from realising the potential of Artificial Intelligence (AI). Here, they explain how we can reap the rewards of this powerful technology in a responsible and ethical way – and accelerate the delivery of new medicines and vaccines to patients. </strong></p>\n<p>Fear of AI is nothing new.</p>\n<p>In fact, it can be traced back to the earliest stages of AI development during the late 20<sup>th</sup> century, when the promise of intelligent machines simultaneously fascinated and alarmed futurists.  </p>\n<p>But that didn’t stop it from progressing, and the 21<sup>st</sup> century has seen the emergence of new AI technologies that demonstrate unprecedented capabilities. At the forefront of this lies the sudden but significant spike in the capabilities of large language models – most famously showcased through the abilities of ChatGPT.</p>\n<p>Trained using huge amounts of data, such models have introduced a step change in the reasoning and productivity power afforded by AI. At GSK, AI means we can build a more complete picture of human health and disease. It allows us to generate and process vast amounts of biological and clinical data so that we can uncover complex patterns and trends that help guide drug discovery and development – from early stage research through to clinical trials.</p>\n<p>Yet the rapid evolution of these technologies has also raised questions about accountability – and fed into broader concerns around job displacement, and the ability of AI to match or even surpass human intelligence. In reality the technology falls short of AI that has intellect, self-awareness and consciousness at a level equivalent to humans <span><span class=\"ui-provider ec bju bge clt clu clv clw clx cly clz cma cmb cmc cmd cme cmf cmg cmh cmi cmj cmk cml cmm cmn cmo cmp cmq cmr cms cmt cmu cmv cmw cmx cmy\">– currently and for the foreseeable future. </span></span></p>\n<p>Even so, these fears have led to demands to halt AI development altogether – some of them without a critical examination of the potential negative consequences to society this could provoke. Concerns have also influenced regulations such as that of the <a href=\"https://www.europarl.europa.eu/news/en/press-room/20230505IPR84904/ai-act-a-step-closer-to-the-first-rules-on-artificial-intelligence\">EU AI Act</a>, which will impose tight restrictions on AI development across the entire EU economy – a move that has been <a href=\"https://www.ft.com/content/9b72a5f4-a6d8-41aa-95b8-c75f0bc92465?desktop=true&amp;segmentId=7c8f09b9-9b61-4fbb-9430-9208a9e233c8#myft:notification:daily-email:content\">met with some criticism</a>.</p>\n<p>It is our belief that calls to halt or significantly delay progress across all areas – including AI use in healthcare – may risk doing more harm than good.</p>\n<h2>Realising the benefits</h2>\n<p>Placing undue limitations on AI development could distract from real challenges that exist because of improper use and creation. For example, AI has been used to spread misinformation, and some of it trained with human biases and discriminatory values that could impact the data it produces.</p>\n<p>It could also deny potential societal benefits to humanity. Rather than replace people in the workplace, for example, <a href=\"https://www.bbc.co.uk/news/business-66248125\">AI could greatly improve productivity</a> and even create better paid, more specialised jobs if utilised effectively.</p>\n<p>In healthcare, AI is transforming diverse functions, improving administrative workflows, surgical safety, health monitoring, precision medicine and preventive care. According to Harvard’s School of Public Health, using AI to make diagnoses may reduce treatment costs by up to 50% and improve health outcomes by 40%.</p>","useGreyBackground":false,"fullWidth":false},{"type":"related-read-content","title":"Read related","relatedPage":{"title":"Modern technologies are doubling the odds of scientists making life-changing medical discoveries","image":{"src":"/media/3okf1kar/microsoftteams-image-9.png?format=webp&v=1dba2eb9f06d140&hmac=41c25d8ed424b1f2bcb3f1a828bfed082ecac5c9d87e137d45c4d51d8655430d","alt":"Scientists working in lab","darkModeSrc":"/media/3okf1kar/microsoftteams-image-9.png?format=webp&quality=50&v=1dba2eb9f06d140&hmac=840b91ea1151992b843420fdd6cb2cc738ca2ab70b21cdb02d8ca0fe5dc60907"},"link":{"text":"new technology drug targets rna medicine development","href":"/en-gb/behind-the-science-magazine/new-technology-drug-targets-rna-medicine-development/","openInNewWindowText":null},"label":"Behind the Science magazine","authorName":null}},{"type":"rich-text","text":"<p>The AI-powered systems that we are currently developing at GSK enable large-scale molecular data to be managed and analysed so that we can better identify causal disease associations and identify new therapeutic strategies, accelerating the discovery of potential drugs, and ultimately getting vaccines and medicines to patients who need them faster than we’ve ever been able to before.</p>\n<p>Such remarkable capabilities already have the power to save countless lives. We can only begin to imagine what we can achieve for patients in the future if such progress is allowed to continue unrestrained by knee-jerk restrictions.</p>\n<h2>A fine balance</h2>\n<p>So, the question arises: how do we balance the risks of developing AI with the incredible benefits?</p>\n<p>We believe the key lies in putting human accountability at the centre of the technology and acknowledging that an AI algorithm or system cannot replace human judgment.</p>\n<p>Tools need to be designed, deployed, and used with good intention. The best way to achieve this is to bake safe and ethical values and practices into every stage of development. Top-down governance and independent regulation could provide human oversight and hold individual users and developers to account.</p>\n<p>Human interpretation of AI-generated predictions and validation of the results is also essential to ensure that ethical and safety standards are upheld. In healthcare, there is already a huge safety net in place for drug development. New medicines and vaccines undergo rigorous testing to ensure that they are safe and effective for patients. Now, we need that same rigor to be applied the evidence generated by AI in healthcare so it can be managed responsibly.</p>","useGreyBackground":false,"fullWidth":false},{"type":"related-read-content","title":"Read related","relatedPage":{"title":"Biomarker testing is helping doctors find precision treatments for patients that could dramatically improve health outcomes","image":{"src":"/media/yy1mgkpn/gsk_oncology_t_cell_6k_rgb.jpg?format=webp&v=1dba2eb9e280a00&hmac=4b01b59932df69c0f1fc98c4e9e404e0814ff34bbde6344e4f45e910168bad00","alt":"T-cell therapy pictured","darkModeSrc":"/media/yy1mgkpn/gsk_oncology_t_cell_6k_rgb.jpg?format=webp&quality=50&v=1dba2eb9e280a00&hmac=a9574f7fdae4913647d9ee4af7ac33174407c1eade6bf58eb9acda73976d7bb5"},"link":{"text":"biomarker testing AI tumours hepatitis respiratory cancer","href":"/en-gb/behind-the-science-magazine/biomarker-testing-ai-tumours-hepatitis-respiratory-cancer/","openInNewWindowText":null},"label":"Behind the Science magazine","authorName":null}},{"type":"rich-text","text":"<p>Appropriate governmental regulation is also needed to weigh up potential risks, protect public safety and manage the rate at which AI technologies are integrated into society.</p>\n<p>Rather than blanket regulations as seen in the EU AI Act, we advocate for a more sophisticated approach where sector-specific regulators – such as existing health regulators – are empowered to establish regulations that balance unique risks and opportunities in each domain.</p>\n<p>Instead of succumbing to thinking in simplistic extremes, we must instead rise to the challenge of safely and effectively harnessing technological progress to best serve the interests of individuals and society. </p>","useGreyBackground":false,"fullWidth":false},{"type":"varied-signpost-grid","title":"","layoutPattern":4,"pages":[{"title":"‘The roar I hear is the next stage of the rocket firing’: MAPS technology and the new age of vaccine development","content":"Researchers are testing new ways to protect against infectious disease – and pursuing effective vaccines that have eluded them for decades.","image":{"src":"/media/jlsdfeti/vaccine-manufacturing-production-line-2.jpg?width=427&height=533&format=webp&quality=100&v=1dba2eb951aafd0&hmac=35f096d6124fdb22be59ec6a26e9429c0c44be93c4c23e34cb4f9c7400d977a7","alt":"Vaccine Manufacturing Production Line","darkModeSrc":"/media/jlsdfeti/vaccine-manufacturing-production-line-2.jpg?width=427&height=533&format=webp&quality=50&v=1dba2eb951aafd0&hmac=fb3ed72121cbbceb7967668fd6b0f055c59a7686976853bd7e4feeade4474a8d"},"link":{"text":"MAPs technology new age vaccine development infectious diseases","href":"/en-gb/behind-the-science-magazine/maps-technology-new-age-vaccine-development-infectious-diseases/","openInNewWindowText":null}},{"title":"‘It’s insidious and it’s getting worse’: AMR and the urgent need for novel antibiotics","content":"The world needs new antibiotics to combat AMR pathogens – but too few are invested in development.","image":{"src":"/media/nd0iyil0/scientist-working-in-working-tb-rd-laboratory-at-gsk-tres-cantos-site-5.png?width=427&height=533&format=webp&quality=100&v=1dbc666f4366150&hmac=4da105e56f483548249e826e96ebe14e3ea79d6ec9fd7013db5bd7774ea287fd","alt":"Scientist working in a lab","darkModeSrc":"/media/nd0iyil0/scientist-working-in-working-tb-rd-laboratory-at-gsk-tres-cantos-site-5.png?width=427&height=533&format=webp&quality=50&v=1dbc666f4366150&hmac=ec8190caf9cb593d0efe4b6527577158384a53474b59939747a5b024b406d2f6"},"link":{"text":"amr antibiotics resistance superbugs new medicines","href":"/en-gb/behind-the-science-magazine/amr-antibiotics-resistance-superbugs-new-medicines/","openInNewWindowText":null}},{"title":"How representation in clinical trials improves health outcomes for women","content":"Until recently, medicines and vaccines were mainly tested on men, which has had a detrimental effect on women’s health globally.","image":{"src":"/media/uu0bxjyq/early-talent-in-a-lab.jpg?width=427&height=533&format=webp&quality=100&v=1dba2eba208edb0&hmac=e0133d0afbbc2d7bba2c1f86de0d31922290957880ee447924d1336d8a5b662a","alt":"Young scientists in a lab","darkModeSrc":"/media/uu0bxjyq/early-talent-in-a-lab.jpg?width=427&height=533&format=webp&quality=50&v=1dba2eba208edb0&hmac=8a421d6bbcf957b8c96afb827fb5f8f1cbff4917d2ec435afe30fc07dac0eccb"},"link":{"text":"men women gender diversity clinical trials","href":"/en-gb/behind-the-science-magazine/men-women-gender-diversity-clinical-trials/","openInNewWindowText":null}}],"hidePageDescription":true,"useGreyBackground":false}]},"id":6364,"docCheckLogout":null,"pageType":"magazinePage","languageCode":"en-GB","theme":"light","breadcrumb":{"ariaLabel":"Breadcrumb","links":[{"text":"Home","href":"/en-gb/","openInNewWindowText":null},{"text":"Behind the Science magazine","href":"/en-gb/behind-the-science-magazine/","openInNewWindowText":null},{"text":"‘AI has already transformed medical innovation. Let’s not let fears of technology stop us from realising its incredible potential’","href":"/en-gb/behind-the-science-magazine/ai-medical-innovation-ethics-responsibility/","openInNewWindowText":null}]},"pageName":"‘AI has already transformed medical innovation. Let’s not let fears of technology stop us from realising its incredible potential’","topNav":{"homeLink":{"text":"GSK Homepage","href":"/en-gb/","openInNewWindowText":null},"topBar":{"currentLocation":{"isGlobal":true,"text":"Global"},"languageSelector":{"currentLanguage":null,"currentLanguageMobile":null,"selectableLanguages":[]},"darkModeSwitch":{"text":"Dark mode","tooltipText":"<p>Switch to dark mode to head towards a more sustainable world together. <a href=\"/en-gb/digital-sustainability/#\" title=\"Digital sustainability\" data-anchor=\"#\">More info</a></p>"},"globalSiteLink":null,"locationSelector":{"text":"Change location","href":"/en-gb/locations/","openInNewWindowText":null},"healthCareLink":{"text":"Healthcare professionals","href":"https://www.gskpro.com","target":"_blank","openInNewWindowText":"Opens in a new window"},"contactUs":{"text":"Contact us","href":"/en-gb/contact-us/","openInNewWindowText":null},"search":"Search","backToMain":"Back to 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Let\\u2019s not let fears of technology stop us from realising its incredible potential\\u2019\",\"keywords\":\"Early Science and Technology,AI\",\"articleBody\":\"There has always been fear about new technologies, argue GSK\\u2019s leading AI experts Kim Branson, Robert Vandersluis and Jeremy England, but that shouldn\\u2019t hold us back from realising the potential of Artificial Intelligence (AI). Here, they explain how we can reap the rewards of this powerful technology in a responsible and ethical way \\u2013 and accelerate the delivery of new medicines and vaccines to patients.\\u00A0Fear of AI is nothing new.In fact, it can be traced back to the earliest stages of AI development during the late 20th century, when the promise of intelligent machines simultaneously fascinated and alarmed futurists.\\u00A0\\u00A0But that didn\\u2019t stop it from progressing, and the 21st century has seen the emergence of new AI technologies that demonstrate unprecedented capabilities. At the forefront of this lies the sudden but significant spike in the capabilities of large language models \\u2013 most famously showcased through the abilities of ChatGPT.Trained using huge amounts of data, such models have introduced a step change in the reasoning and productivity power afforded by AI. At GSK, AI means we can build a more complete picture of human health and disease. It allows us to generate and process vast amounts of biological and clinical data so that we can uncover complex patterns and trends that help guide drug discovery and development \\u2013 from early stage research through to clinical trials.Yet the rapid evolution of these technologies has also raised questions about accountability \\u2013 and fed into broader concerns around job displacement, and the ability of AI to match or even surpass human intelligence. In reality the technology falls short of AI that has intellect, self-awareness and consciousness at a level equivalent to humans \\u2013 currently and for the foreseeable future.\\u00A0Even so, these fears have led to demands to halt AI development altogether \\u2013 some of them without a critical examination of the potential negative consequences to society this could provoke. Concerns have also influenced regulations such as that of the EU AI Act, which will impose tight restrictions on AI development across the entire EU economy \\u2013 a move that has been met with some criticism.It is our belief that calls to halt or significantly delay progress across all areas \\u2013 including AI use in healthcare \\u2013 may risk doing more harm than good.Realising the benefitsPlacing undue limitations on AI development could distract from real challenges that exist because of improper use and creation. For example, AI has been used to spread misinformation, and some of it trained with human biases and discriminatory values that could impact the data it produces.It could also deny potential societal benefits to humanity. Rather than replace people in the workplace, for example, AI could greatly improve productivity and even create better paid, more specialised jobs if utilised effectively.In healthcare, AI is transforming diverse functions, improving administrative workflows, surgical safety, health monitoring, precision medicine and preventive care. According to Harvard\\u2019s School of Public Health, using AI to make diagnoses may reduce treatment costs by up to 50% and improve health outcomes by 40%.The AI-powered systems that we are currently developing at GSK enable large-scale molecular data to be managed and analysed so that we can better identify causal disease associations and identify new therapeutic strategies, accelerating the discovery of potential drugs, and ultimately getting vaccines and medicines to patients who need them faster than we\\u2019ve ever been able to before.Such remarkable capabilities already have the power to save countless lives. We can only begin to imagine what we can achieve for patients in the future if such progress is allowed to continue unrestrained by knee-jerk restrictions.A fine balanceSo, the question arises: how do we balance the risks of developing AI with the incredible benefits?We believe the key lies in putting human accountability at the centre of the technology and acknowledging that an AI algorithm or system cannot replace human judgment.Tools need to be designed, deployed, and used with good intention. The best way to achieve this is to bake safe and ethical values and practices into every stage of development. Top-down governance and independent regulation could provide human oversight and hold individual users and developers to account.Human interpretation of AI-generated predictions and validation of the results is also essential to ensure that ethical and safety standards are upheld. In healthcare, there is already a huge safety net in place for drug development. New medicines and vaccines undergo rigorous testing to ensure that they are safe and effective for patients. Now, we need that same rigor to be applied the evidence generated by AI in healthcare so it can be managed responsibly.Appropriate governmental regulation is also needed to weigh up potential risks, protect public safety and manage the rate at which AI technologies are integrated into society.Rather than blanket regulations as seen in the EU AI Act, we advocate for a more sophisticated approach where sector-specific regulators \\u2013 such as existing health regulators \\u2013 are empowered to establish regulations that balance unique risks and opportunities in each domain.Instead of succumbing to thinking in simplistic extremes, we must instead rise to the challenge of safely and effectively harnessing technological progress to best serve the interests of individuals and society.\\u00A0\",\"articleSection\":\"Behind the Science magazine - Opinion\"}"]}}