We are one of the biggest contributors to Singapore's biomedical sciences industry with investments in excess of S$1.5 billion.
Singapore is the regional headquarters of our Emerging Markets and Asia Pacific pharmaceutical and consumer healthcare businesses.
As well as global, regional and local commercial operations, we have a significant manufacturing presence in Singapore, comprising two global manufacturing supply sites and a vaccines manufacturing facility.
We were the first global healthcare company to establish a presence in Singapore. In the years since, we have forged strong and mutually beneficial partnerships to grow our business, develop talent and contribute to Singapore's thriving biomedical sciences industry.
Today we employee around 1,900 people in Singapore, every one of whom share our mission to help people do more, feel better and live longer.
Our sites in Singapore
In Singapore, our business is spread across four sites – two global manufacturing supply sites, a vaccines manufacturing facility and our corporate and commercial office.
GSK Asia House
Corporate and commercial offices
GSK Asia House is the regional headquarters of our Emerging Markets and Asia Pacific pharmaceutical and consumer healthcare businesses. It is also the global headquarters of our Classic and Established Products group and home to our commercial operations for the Singapore market.
Jurong global manufacturing site
Our Jurong site opened in 1982. The site, which now sits on a nine-hectare site, has evolved from bulk manufacture of established products in the early days to becoming a leading new product introductions (NPI) site within our pharma supply chain, producing new innovative medicines including dolutegravir and the new product, daprodustat.
It is focused on the development of late phase new chemical entities (NCEs) and delivering higher value products such as very active compounds in small batch sizes. The site currently has an R&D Pilot Plant where NCEs are developed and scaled up, and three production buildings making 13 active pharmaceutical ingredients for a range of medicines prescribed for the treatment of respiratory, oncology, allergy, anti-viral and neurological conditions.
In 2014, the Jurong site built a commercial continuous processing plant using new hybrid continuous-batch synthesis, the first of its kind within our pharma supply chain. In 2019, the site opened new production facilities worth S$130m, including two continuous manufacturing facilities, and an expansion of one of the site’s production buildings.
Quality road global manufacturing site
Quality Road is one of the world’s largest amoxicillin facilities and Singapore’s first pharmaceuticals manufacturing plant. Built in 1972 at a cost of over S$32 million, the site was officially opened in May 1973.
The site was originally built to produce a range of newly discovered semi-synthetic penicillin and had both primary and secondary production facilities to make the final dose forms. The site was originally built to produce a range of newly discovered semi-synthetic penicillins and had both primary and secondary production facilities to make the final dose forms. Over time, the site developed as the single source of amoxicillin within GSK, which is an active compound for the manufacture of our antibiotics.
In 2012, we invested S$60 million to improve antibiotic manufacturing capabilities by utilising enzymatic technology to replace existing chemical processes during the production of amoxicillin. In 2015, S$77million was invested to construct an additional facility for enzymatic manufacturing.
Tuas global vaccines manufacturing facility
With an investment of S$510 million, our state-of-the-art vaccines manufacturing facility at Tuas was opened in June 2009 by Singapore's Prime Minister Lee Hsien Loong, coinciding with our 50th anniversary in Singapore.
Comprising two production buildings, an administration block, quality control laboratories, utility plant and warehousing, the facility became operational in 2011. The facility and operations meet the high quality and good manufacturing standards of global regulatory bodies such as the European Medicines Agency.
Tuas is the sole manufacturing site within our network supplying the active ingredient used to make our pneumococcal conjugate vaccine, Synflorix™, This paediatric vaccine is indicated for the active immunisation against pneumonia caused by Streptococcus pneumoniae, invasive diseases and acute otitis media caused by Streptococcus pneumoniae in infants and children.
Following the success of Synflorix™, the manufacture of HiB (Haemophilus influenzae type b) antigen was transferred to the site. This antigen is used in the manufacture of several paediatric vaccines, such as Hiberix™ and Infanrix Hexa™. Haemophilus influenzae type b (Hib) is a bacterium responsible for invasive diseases, such as severe pneumonia and meningitis, contracted almost exclusively by children less than five years old. The site will be the sole supplier of HiB bulk production from 2020.
These two vaccine products manufactured at Tuas covers approximately 45% of the diseases causing paediatric mortality in the world, making a significant contribution to our global health agenda. The site continues to invest in developing technical capability and process improvement, and embracing new technology such as digital, data and analytics to position itself as the centre of excellence for the manufacture of vaccines.
Health professionals in Singapore can obtain information about products and areas of therapy related to GSK by visiting GSKPro
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