GSK today announced progress on its commitment to share more detailed data from its clinical trials.
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\nGlaxoSmithKline (GSK) today announced progress on its commitment to share more detailed data from its clinical trials. A new online system available on gsk.com (https://clinicalstudydata.gsk.com/) will enable researchers to request access to anonymised patient level data that sit behind the results of clinical trials. It is hoped that sharing these data with researchers will help to further scientific research, increase understanding of new and current medicines and ultimately improve patient care.
\nConsistent with expectations of good scientific practice, researchers can request access by providing a scientific protocol with a commitment to publish their findings. External independent experts appointed by GSK to advise on the development of the system will be the initial review panel, responsible for assessing research proposals made through the system.
Access to the data from GSK’s studies will be provided on a password protected website to help protect research participants’ privacy and ensure the data are used for the approved scientific purpose.
This initiative is a step towards the ultimate aim of the clinical research community developing a broader system where researchers are able to access data from clinical trials conducted by multiple organisations. This system would be run by an independent third party who would be responsible for appointing and overseeing a review panel to assess research proposals. GSK is already in discussions with interested parties to encourage the development of such a system.
\nPatrick Vallance, GSK’s President of Pharmaceuticals R&D, said: “When people volunteer for clinical trials they expect that the results will be used to help others. We are absolutely committed to sharing data so that researchers can examine the details more closely, do their own analyses and learn more about medicines and how they can best be used. Consistent with good scientific practice, researchers will be required to submit a research plan and to commit to transparency in the publication of their work.
\n“We are the first organisation to develop a system for sharing detailed clinical data in this way. Now we want to see this initiative transition to a broader independent model that brings together data from multiple organisations. We are keen for this to progress and hope such a system can be put in place by a third party in the public or charitable sector as soon as possible.”
\nStudies will be listed on GSK’s system once a medicine has been approved by regulators or terminated from development and the study has been accepted for publication. Studies that do not progress to publication will also be included. The system already includes global studies conducted since 2007. Over the next two years global studies going back to the formation of GSK in December 2000 will be added. In addition, all studies (including local studies) starting in or after 2013 will be included.
\nGSK has taken a number of steps over the years to share more information from clinical trials that evaluate its medicines:
\n| \n Brian L. Strom MD (Chairman) \n | \n\n George S Pepper Professor of Public Health and Preventive Medicine, Professor of Biostatistics and Epidemiology, and Executive Vice Dean for Institutional Affairs, Perelman School of Medicine, University of Pennsylvania, United States \n | \n
| \n Marc Buyse ScD \n | \n\n Associate Professor of Biostatistics, Hasselt University Belgium and Founder, International Drug Development Institute, United States \n | \n
| \n Bartha Maria Knoppers PhD \n | \n\n Canada Research Chair in Law and Medicine and Director of the Center of Genomics and Policy, McGill University, Canada \n | \n
| \n John Hughes \n | \n\n Patient and Public Involvement member of the UK Clinical Research Collaboration Board, UK \n | \n
Further information about panel members is available on the online system.
\n\n
GlaxoSmithKline – one of the world’s leading research-based pharmaceutical and healthcare companies – is committed to improving the quality of human life by enabling people to do more, feel better and live longer. For further information please visit www.gsk.com
\n| \n GlaxoSmithKline Enquiries: \n | \n\n | \n | \n |
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| \n \n | \n\n \n | \n\n \n | \n\n \n | \n
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| \n \n | \n\n | \n | \n |
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| \n Cautionary statement regarding forward-looking statements | \n
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