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Manufacturing and supply

Manufacturing and supply at GSK

Making our medicines, vaccines and consumer healthcare products, and ensuring they are safe and of the highest quality, is a huge responsibility. It drives us to innovate across every stage of the process. This means we embrace a modern approach to manufacturing and supply – like piloting continuous manufacturing at our Jurong site in Singapore which ensures fast and high-quality delivery.

Continuous manufacturing pilot project, Jurong (Singapore)

Producing our medicines in the most efficient way while not compromising our high standards is important as it means we can get them to patients more quickly.

Take a look around our continuous manufacturing pilot project in Jurong, Singapore.

Transcript

My work on a day-to-day basis involves a good mix of design as well as commissioning, as well as a bit of problem solving, so it keeps things interesting.

I am the project lead for GSK's first continuous primary manufacturing project and the factory here in Singapore at Jurong.

GSK has an ambition to have at least 50% of new products to have some form of continuous manufacturing.

In continuous manufacturing, input materials are added continuously in the system and at the same time, product is removed. Whereas in batch manufacturing, input materials are added at one time and the product removed all at once at the end of manufacturing. "

I've worked at GSK since 1997 as a Utilities Technician, running our boilers and incinerators.

My role in this project is to implement the continuous FP (fluticasone propionate) process and also to supervise a group of junior technicians.

As part of this role, I picked up a lot of new technical and operational skills in R&D (Stevenage, UK).

The highlight for me on this project was to work together with various parties and teams from different countries and different sites for example, R&D in Stevenage as well as our partners in Zeton in Holland to implement GSK's innovative manufacturing technologies on-site here in Singapore.

We are now able to make fluticasone propionate in a safer, faster and more efficient way.

At the age of 52, I was very happy that the company still sent me for overseas training to take on the new challenge and new technology.

All the overseas training at Zeton and Stevenage made it much easier for me to train and share the knowledge, operational and technical details with my junior technicians.

Continuous manufacturing is significantly different from batch manufacturing in many areas. So this is a pilot project for Jurong because it has enterprise-wide impact in the way the facility is designed, operated, maintained and calibrated.

Projects like this are important because they represent a step-change up from our current way of manufacturing via a batch process. They enable us to focus on our performance to deliver better value for the patient by manufacturing faster, more efficiently and safer.

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