Research and development approach

We will get ahead of disease together with our R&D focus on the science of the immune system and advanced technologies.

Scientists talking and laughing in a lab

R&D is the core of our innovation

In 2022, we invested £5.5 billion in R&D – 9% AER more than 2021 - to enhance our pipeline of vaccines and medicines and help us get ahead of disease together.

Our scientists prioritise genetically identified targets that are at least twice as likely to succeed in the clinic.  They also prioritise infectious disease targets and immune-modulators that have greater lifecycle opportunities. 


How our R&D approach is getting us ahead of disease

  • Vaccines and medicines currently in development

  • Major new vaccines and medicines approved since mid 2017

  • Number of assets in phase III/registration in 2022

  • Number of phase I programmes started in 2022


Why do we prioritise genetically validated targets in our R&D?

Scientist in the lab with globes on

Scientific research shows that genetically validated targets are at least twice as likely to successfully become medicines.

What therapeutic areas are we focusing on?

We prioritise research into vaccines and medicines across our four core therapeutic areas of infectious diseases, HIV, respiratory/immunology, and oncology. We also remain open to opportunities outside of these core areas where the science aligns with our strategic approach. We continue to strengthen our pipeline of vaccines and medicines, applying our growing expertise and partnerships in technology and data to increase the productivity of our R&D.